History:

A 67-year-old woman presented with right-sided neck pain. Examination revealed a nodular mass near the parotid gland, and imaging showed a 3.0 cm mass involving the gland. FNA suggested a basaloid neoplasm. Parotidectomy specimen: a pale tan, irregularly bordered mass lying very close to the surgical margin. Histology showed a basaloid neoplasm (image). Immunohistochemistry: Positive: pancytokeratin, SOX10, and focal CD117, p63 and p40; Negative: β-catenin, p16, high-risk HPV ISH, PLAG1 and RAS p.Q61R